Restylane, Profhilo or Sunekos for Your Neck? A GP Explains the Difference
Main image – Dianevilladsen/Stocksy
Dr Sonia Khorana is a GP with a special interest in dermatology and Live That Glow’s own skincare agony aunt. She is passionate about helping people feel confident in their own skin. In this month’s column, she advises on skin boosters for neck ageing. Got a question for Dr Sonia? Send it to columnists@livethatglow.com for a chance to have it featured.
I’ve started to notice some crepiness in my neck, and my necklace lines are also getting deeper. My dermatologist has recommended Restylane as a “skin booster”, but I don’t really know what that means or how effective it would be. I’ve also seen good things about Profhilo, but I don’t understand what the difference is between all these different treatments and what they can achieve.
Dr Sonia says:
What your dermatologist is referring to with Restylane Skinboosters is a category of injectable treatments designed to improve skin quality rather than to “fill” or change facial structure in a traditional sense.
Restylane Skinboosters are injectable moisturisers that boost elasticity and improve skin texture and roughness. They work by replenishing hyaluronic acid in the skin, which naturally depletes as part of the ageing process. By restoring these hydration levels, they also help support the formation of new collagen and elastin, which is why they can be particularly helpful for early crepiness and fine lines, especially in delicate areas like the neck. A course of around three treatments is usually recommended initially, and results can last around 6–12 months.
Profhilo is another popular option in this category – it’s more of a “bio-remodelling” injectable that spreads under the skin and can help improve hydration as well as stimulate collagen and elastin. In clinic, I do find it a really effective treatment for overall skin quality and early laxity, particularly for the neck and lower face, but it’s important to be very honest about expectations. These treatments soften and improve crepiness rather than erase deeper necklace lines completely.
Other treatments such as Sunekos take a slightly different approach again, combining hyaluronic acid with amino acids to help stimulate fibroblast activity and support collagen production. These can be particularly useful when the goal is not only hydration but also improving the underlying quality and resilience of the skin over time.
The most important thing to understand is that skincare still forms the foundation. A good routine – especially daily sunscreen, alongside ingredients like retinoids and antioxidants helps maintain skin health and protect collagen long term.
However, skincare can only penetrate so deeply into the skin. That’s where injectable treatments come in: they work within the dermis, where collagen and elastin are actually made, to improve hydration, structure, and overall skin quality in a way topical products simply can’t achieve alone.
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