‘Exosomes’ are Still Trending. But Do You Really Need to Bother with Them?

Share the love!

Main image – Olgamurzaeva/Stocksy

When it comes to skincare, there are loads of terms you’ll probably recognise straight away, yet there are still some that might as well be in a foreign language.

Prime example: For some, the word ‘exosomes’ might be leaning towards the latter, because frankly, exo…what?

And given that lots of people still don’t know what this trending ingredient is, do we really need to bother jumping on the exosomes train? What do they actually do? And how do they benefit the skin?

We asked dermatologist Dr Hannah Kopelman and skincare expert Jessica Kerr for their take on why ‘exosomes’ might just be worth investing in and how we should use them safely and efficiently.

What are exosomes?

“Exosomes are tiny, naturally occurring vesicles released by cells,” explains Kerr. “Think of them as messengers, carrying proteins, lipids, and genetic material between cells to help regulate processes like tissue repair and immune responses. In skincare, they’re hailed for their potential to enhance skin health and regeneration.”

various cosmetic creams | Live That Glow

Image – Adobe

Dr Kopelman adds, “They’re fascinating because they essentially help your body’s cells “talk” to each other to repair damage and improve tissue health.”

How can exosomes benefit your skin?

Turns out, they’re a bit of a game changer. “They boost collagen production, reduce inflammation, and promote cellular repair,” Dr Kopelman says.

“I’ve seen remarkable improvements in my patients’ skin texture, fine lines, and even acne scars. When combined with in-office treatments like microneedling, they can take the results to a whole new level.

“I’ve also used them for hair restoration, and they’ve shown incredible promise in improving hair density and growth.”

Kerr adds, “they’re particularly effective in targeting signs of ageing, uneven skin texture, and other concerns by supporting the skin’s natural ability to heal and rejuvenate.”

How are they used topically in skincare?

“You’ll mostly find exosomes in advanced skincare serums and creams,” Dr Kopelman explains. Kerr says you can find them in post-treatment recovery products too. “Their lightweight molecular structure makes them ideal for formulations aimed at deep skin penetration,” she says.

Portrait of curly-haired woman | Live That Glow

Image – Michelaravasio/Stocksy

So how do you know if a product contains them? “[They] are usually very clear about it because it’s a big selling point,” Dr Kopelman says.

“Look for terms like “exosome technology” or “stem cell-derived exosomes” on the label or in the product description. I always recommend choosing products from trusted brands that provide transparency about their sourcing and testing.”

How are exosomes used in office?

“They are often included in advanced skin treatments like microneedling or laser therapies to enhance recovery and results,” Kerr explains.

But is it safe? “In my experience, exosomes are safe when they’re sourced from reputable manufacturers and used by trained professionals,” Dr Kopelman adds.

“I’ve treated numerous patients with exosome therapies and rarely encounter issues. That said, quality and handling are crucial—so working with an experienced provider is essential to ensure safety.”

What age should you start using exosomes?

“Exosomes are ideal for anyone looking to address early signs of aging, improve skin texture, or even stimulate hair growth,” says Dr Kopelman. And she says you could start using them as early as in your 20s.

“Exosomes can be a great addition to a skin rejuvenation routine starting in your late 20s to early 30s, especially if you’re beginning to notice early signs of aging or experiencing skin concerns like dullness, fine lines, or inflammation,” she explains.

Image – Studiofirma/Stocksy

“That said, age isn’t the only factor—it’s more about the condition of your skin. If someone has sun damage, acne scars, or is recovering from procedures like microneedling or laser, exosomes can accelerate healing and boost results.”

So what’s the difference between topical and medical, and which option should we go for first? “At-home versions are typically more gentle, while in-office treatments are more concentrated and regenerative, so I usually recommend starting with in-office options under guidance before investing in home care,” Dr Kopelman advises.

How to use exosomes safely

Finding a reputable clinician is key. “Look for a board-eligible dermatologist or aesthetic doctor with experience in regenerative medicine or cosmetic dermatology,” says Dr Kopelman.

“Exosome treatments are still relatively new, so it’s essential the provider uses high-quality, well-sourced products and can explain the science behind them.

“Don’t be afraid to ask where the exosomes come from, whether they’re tested for purity and safety, and what kind of training the provider has. Reviews, before-and-after photos, and word-of-mouth recommendations can also be helpful.”

To apply them topically, she recommends slotting them in after your cleanse. “Apply exosome-based products after cleansing and before moisturising – much like a serum,” she says. So if your serum contains exosomes then this would be the perfect time.

“Use them as part of your serum step, both morning and evening, for best results. Some are formulated for post-treatment recovery and should be used as directed by your aesthetician or skincare professional,” Kerr adds.

Who should avoid using them?

Whilst exosomes are suitable for most skin types, “people with extremely sensitive or reactive skin should consult a dermatologist before introducing exosomes into their routine,” warns Kerr. Are there any risks otherwise?

“The primary risk lies in the sourcing and processing of exosomes,” she adds. “Poorly regulated products may introduce impurities or cause adverse reactions. Always choose reputable brands and avoid products that don’t disclose their ingredients transparently.”

And Dr Kopelman says any research on exosomes is still young. “While exosomes are generally safe when sourced and used properly, we do need to acknowledge that the long-term effects are not fully understood yet,” she explains.

“This is still an emerging area in dermatology, and we don’t have decades of data to assess potential risks over time.

“The dermatology community is somewhat divided on the use of exosomes, with some experts fully embracing their potential and others urging caution until more robust, long-term studies are available. In my practice, I’m careful to use only well-vetted products and treatments, but I always discuss this uncertainty with my patients so they can make an informed decision.”

The takeaway

So do we really need to bother with exosomes? Well, looking at the benefits these little skin messengers can give your skin – improved skin texture, boosting collagen production, reducing inflammation and targeting signs of ageing – perhaps we shouldn’t write them off just yet.

Typically, you’ll slot exosomes into your routine after cleansing at home or you can also have them applied professionally, as long as you find a reputable clinician. Those with sensitive or reactive skin should stay clear but otherwise, the experts haven’t yet come across any evidence that they’re not safe to use once or twice a day.

So, if you see the words “exosome technology” or “stem cell-derived exosomes” on the label of a product by a brand you trust, it might just be worth seeing for yourself what all the fuss is about.